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Clinical trial of investigational therapy for critical limb ischemia (CLI) HEMATRATE	CellSeal Vial Sample Recovery Instructions CELLSEAL, CLOSED-SYSTEM CRYOGENIC VIALS	HemaTrate® Blood Filtration System FLYERS, HEMATRATE	HemaTrate®: Bring Cell Therapy to Your Patient HEMATRATE, VIDEOS	Stemulate™ Pooled Human Platelet Lysate FLYERS, STEMULATE	nLiven™ PR Pathogen-Reduced Human Platelet Lysate FLYERS, nLIVEN PR
CellSeal® Semi-Automated Filling System CELLSEAL, FLYERS, SAFS-100	CellSeal® SAFS-100 – Instructional Video CELLSEAL, SAFS-100, VIDEOS	CellSeal® AF-500 AF-500, CELLSEAL, FLYERS	CellSeal® AF-500 Instructional Video AF-500, CELLSEAL, VIDEOS	CellSeal® Radio Frequency Tube Sealing System CELLSEAL, FLYERS, RADIO FREQUENCY TUBE SEALING SYSTEM	CellSeal® Closed-System Cryogenic Vials CELLSEAL, CLOSED-SYSTEM CRYOGENIC VIALS, FLYERS
CellSeal® Closed-System Cryogenic Vials – Instructional Video CELLSEAL, CLOSED-SYSTEM CRYOGENIC VIALS, VIDEOS	CellSeal® Vial Diagram CELLSEAL, CLOSED-SYSTEM CRYOGENIC VIALS	CellSeal® Automated Thawing System AUTOMATED THAWING SYSTEM, CELLSEAL, FLYERS	Compass® CT and Compass® CT Port Disposable Pressure Transducer COMPASS CT, FLYERS	ProFusion™ Therapeutic Infusion Needle FLYERS, PROFUSION	Human platelet lysate as a media supplement for ex vivo expansion of immune cells POSTERS, nLIVEN PR
Xeno-Free Cultivation of Mesenchymal Stem Cells From the Corneal Stroma (IOVS, an ARVO Journal, May 2017) HPL, POSTERS	The use of pooled human platelet lysate for isolation and ex vivo expansion of skeletal myoblasts for clinical use (Aalborg Univ. June 2017) HPL, POSTERS	Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study (Stem Cells Translational Medicine July 2017) HPL, POSTERS	Stemulate™ supports differentiation of IPS cell-derived Endothelial Colony-Forming Cells HPL, POSTERS	Human platelet lysate promotes Synovial fluid Mesenchymal Stem Cell proliferation and differentiation CELLSEAL, HPL, POSTERS	The Effects of Common Transient Warming Events on Post Thaw Recovery and Viability of Human Mesenchymal Stem Cells Stored in LN2 Vapour & -80°C Environments CELLSEAL, HPL, POSTERS
A new platelet lysate alternative to serum for ex vivo transduction and expansion of human T cells HPL, POSTERS, nLIVEN PR	Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications REFERENCE ARTICLES, STEMULATE	Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells REFERENCE ARTICLES, STEMULATE	Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow REFERENCE ARTICLES, STEMULATE	Effect of platelet lysate on the functional and molecular characteristics of mesenchymal stem cells isolated from adipose tissue REFERENCE ARTICLES, STEMULATE	Human platelet lysate permits scale-up of dental pulp stromal cells for clinical applications REFERENCE ARTICLES, STEMULATE
Peak serum: implications of serum supply for cell therapy manufacturing REFERENCE ARTICLES, STEMULATE	Human platelet lysate as a fetal bovine serum substitute improves human adipose-derived stromal cell culture for future cardiac repair applications REFERENCE ARTICLES, STEMULATE	Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components REFERENCE ARTICLES, STEMULATE	Pooled human platelet lysate versus fetal bovine serum-investigating the proliferation rate, chromosome stability and angiogenic potential of human adipose tissue-derived stem cells intended for clinical use. REFERENCE ARTICLES, STEMULATE	Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells. REFERENCE ARTICLES, STEMULATE	Senescence and quiescence in adipose-derived stromal cells: Effects of human platelet lysate, fetal bovine serum and hypoxia REFERENCE ARTICLES, STEMULATE
Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate REFERENCE ARTICLES, STEMULATE	Comparative Analysis of Media and Supplements on Initiation and Expansion of Adipose-Derived Stem Cells REFERENCE ARTICLES, STEMULATE	Comparison of clinical grade human platelet lysates for cultivation of mesenchymal stromal cells from bone marrow and adipose tissue REFERENCE ARTICLES, STEMULATE	Rapid and efficient stable gene transfer to mesenchymal stromal cells using a modified foamy virus vector REFERENCE ARTICLES, STEMULATE	Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study REFERENCE ARTICLES, STEMULATE	Amnion derived MSC growth comparison STEMULATE, VIDEOS
The Effect of Storage Temperature and Repetitive Temperature Cycling on the Post Thaw Functionality of Human Mesenchymal Stem Cells HPL, POSTERS, STEMULATE	Scalable Xeno-Free Expansion of Human Mesenchymal Stromal Cells in a Single-Use, Vertical-Wheel Bioreactor System HPL, POSTERS, STEMULATE	Evaluation of Stemulate for the Expansion and Cryopreservation of Human Mesenchymal Stem Cells HPL, POSTERS, STEMULATE	The Role of Human Platelet Lysate in the Cryopreservation of Mesenchymal Stem Cells HPL, POSTERS, STEMULATE	Attaching cells to naturally occurring extracellular matrices prior to cell delivery HPL, POSTERS, STEMULATE	Human platelet lysate supports growth of human skin and vascular-derived cells similar to fetal bovine serum and serum-free media HPL, POSTERS, STEMULATE
Characterization of human platelet lysate in cytokine analysis and proliferative effect on mesenchymal stem cells HPL, POSTERS, STEMULATE	Applications of Cook human platelet lysate in cell therapy HPL, POSTERS, STEMULATE	Freezing and recovery of mesenchymal stem cells in human platelet lysate HPL, POSTERS, STEMULATE	Comparison of human platelet lysate (HPL) and fetal bovine serum (FBS) for optimal culture conditions of neonatal and adult mesenchymal stem cells (MSCs) HPL, POSTERS, STEMULATE	An Aseptic Closed-System Vial System for Cryopreservation Storage of Biomaterials CELLSEAL, POSTERS	Design verification and enhanced risk mitigation for cytocompatibility evaluation of cell delivery devices CELLSEAL, POSTERS
Cytocompatibility evaluation of cell delivery devices using clinically relevant cells under exaggerated use conditions CELLSEAL, POSTERS	A closed system container for shipping non-frozen cellular therapy products for direct clinical use CELLSEAL, POSTERS	Off the shelf cellular therapeutics: Factors to consider during cryopreservation and storage of human cells for clinical use CELLSEAL, POSTERS	Collection, Cryopreservation and Characterization of Human Tooth Derived MSC for Banking and Clinical Use CELLSEAL, POSTERS	A Novel Closed System Vial with Sentinel Test Segment for Sperm Cryopreservation CELLSEAL, POSTERS	A New Cryogenic Container System for Clinical Cryopreservation of Biomaterials CELLSEAL, POSTERS
A cryopreservation system for direct clinical use of MSC CELLSEAL, POSTERS	A new automated vial thawing system controls the RESUSCITATION of cryopreserved mesenchymal stem cells to achieve high cell viability and growth potential CELLSEAL, POSTERS	Less Than 1% Variation in the Fill Accuracy of the SAFS-100 CellSeal® Semi-Automated Filling System (August 2017) CELLSEAL, WHITE PAPERS	Review: The Industry’s Need for Closed-System Cryogenic Storage (November 2017) CELLSEAL, CLOSED-SYSTEM CRYOGENIC VIALS, WHITE PAPERS	Characterization of a Pathogen-Reduced Human Platelet Lysate POSTERS, nLIVEN PR	A method of evaluating cytocompatibility of devices for the delivery of cells COMPASS CT, HEMATRATE, POSTERS, PROFUSION
The use of pooled human platelet lysate for isolation and ex vivo expansion of skeletal myoblasts for clinical use (Aalborg Univ. June 2017) POSTERS, STEMULATE	Endometrial regenerative cell growth comparison STEMULATE, VIDEOS	A new platelet lysate alternative to serum for ex vivo transduction and expansion of human T-cells HPL

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Advancing regenerative medicine therapies

Cook Regentec is focused on developing research and clinical tools to advance regenerative medicine therapies from the lab to the patient. Cook Regentec’s starting range of products includes cellular growth media, solutions for cryopreservation, and medical devices for the delivery of therapeutic agents.